Eyelid Dermatitis Due To Contact Allergy To Cocamidopropyl Betaine

H. D. Oei

Albert Schweitzer Hospital, Dordrecht, THE NETHERLANDS.

Allergic contact dermatitis has been considered the most common of the many dermatologic conditions found with eyelid dermatitis.
Important sources of contact sensitivity include cosmetics (fragrance components, preservatives, emulsifiers, artificial nails and nail lacquer) topical medications , metals, rubber, derivatives, resins and plants. artificial nails and nail lacquer. Eyelid dermatitis is a multifaceted clinical problem. Contact allergy to cocamidopropyl betaine is frequently undiagnosed because clinical awareness is low and because of the absence of this screening allergen in the European Standard Series .
We described 5 cases of cosmetic allergy to cocamidopropyl betaine, all were caused by shampoo or shower gels.
23 patients who came to our allergology clinic with eyelids dermatitis were tested with cocamidopropyl betaine in addition to the ESS.
Readings were taken on day 4.
Cocamidopropyl betaine was supplied by Trolab Hermal.
5 patients showed a positive reaction to cocamidopropyl betaine
We concluded that it is important to do patch tests with cocamidopropyl betaine in all patients with eyelid dermatitis.
Cocamidopropyl betaine appears to be an important contact allergen in cosmetics, especially in shampoos and bath foam and this is an surfactant used increasingly in cosmetic products. Although rinse-off products generally are not associated with allergic contact dermatitis, a surfactant used increasingly in shampoos, bath gels, and similar products can trigger such a reaction.